COLORIMETRIC DETERMINATION OF CERTAIN SYMPATHOMIMETIC DRUGS

A colorimetric method for the determination of certain purine antagonists.

The purine antagonists with which this paper is concerned are of interest in the chemotherapy of neoplastic diseases and belong to either of the two groups: the substituted purines such as 6-mercaptopurine (6MP) (1) and isomers of purines such as 4-aminopyrazolo (3,4-d) pyrimidine (4APP) (2). In connection with their pharmacological studies (3), it is essential to have a method available for th...

Treating anaphylaxis with sympathomimetic drugs.

Adrenoceptor - Activating & Other Sympathomimetic Drugs

The ultimate effects of sympathetic stimulation are mediated by release from nerve terminals of norepinephrine that serves to activate the adrenoceptors on postsynaptic sites. Also, in response to a variety of stimuli such as stress, the adrenal medulla releases epinephrine, which is transported in the blood to target tissues; in other words, epinephrine acts as a hormone. Drugs that mimic the ...

Conductometric Determination of Certain Pharmacological Drugs Using Silver and Bismuth

Two simple, rapid and accurate conductometric methods were developed for determination of losartan potassium, pantoprazole sodium, sumatriptan succinate, rabeprazole sodium and lomefloxacine HCl in pure form as well as in their pharmaceutical formulations. The proposed methods based on using two different precipitating agents for conductometric determination of the cited drugs. Method (A) based...

Determination of phenolic sympathomimetic drugs in pharmaceutical samples and biological fluids by flow-injection chemiluminescence.

A rapid and highly sensitive flow-injection chemiluminometric method was developed for determination of 3 sympathomimetic drugs, namely, etilefrine hydrochloride, isoxsuprine hydrochloride, and prenalterol hydrochloride. The method is based on chemiluminescence induced by oxidation of drugs with acidified potassium permanganate in the presence of formic acid as a carrier. The calibration graphs...